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The type of bladder cancer has implications in selecting the appropriate treatment for the disease.

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Men are more prone to developing bladder cancer probably due to a higher incidence of smoking and exposure to toxic chemicals.

A close relative with a history of bladder cancer may increase the predisposition for the development of this disease.

People who smoke also have a higher risk of many other types of cancer, including acute leukemia and cancers of the lung, lip, mouth, larynx, esophagus, stomach, and pancreas.

Smokers also have a higher risk of diseases like heart attacks, peripheral vascular disease, diabetes, stroke, bone loss (osteoporosis), emphysema, and bronchitis.

From time to time, the muscular wall of the bladder contracts to expel urine through the urinary passage (urethra) into the outside world.

The normal volume of the full bladder is about 400 ml-600 ml, or about 2 cups. The innermost layer of the bladder, which comes into contact with the urine stored inside the bladder, is called the "mucosa" and consists of several layers of specialized cells called "transitional cells," which are almost exclusively found in the urinary system of the body.The longer and heavier the exposure, greater are the chances of developing bladder cancer.The toxic chemicals in cigarette smoke, many of which are known cancer-causing substances (carcinogens), travel in the bloodstream after being absorbed from the lungs and get filtered into the urine by the kidneys.Its primary function is to store urine that drains into it from the kidney through tube-like structures called the ureters.The ureters from both the kidneys open into the urinary bladder.They then come in contact with the cells in the inner lining of the urinary system, including the bladder, and cause changes within these cells that make them more prone to developing into cancer cells.